$25 Million Gift From the Smilow Foundation to Establish the Smilow Center for Precision Therapeutics at Penn Medicine

A $25 million gift from the Smilow Foundation, led by William Smilow, will establish the Smilow Center for Precision Therapeutics at Penn Medicine. The Center will advance gene-editing and other precision therapies designed to address the underlying causes of cardiovascular disease.
“The Smilow Foundation has made an extraordinary commitment to advancing groundbreaking research with the potential to achieve what was once considered impossible: curing previously debilitating forms of heart disease,” said Jonathan A. Epstein, dean of Penn’s Perelman School of Medicine and Executive Vice President of University of Pennsylvania for the Health System. “Their support empowers our researchers to harness transformative innovations to redefine the future of cardiovascular medicine and strengthen Penn Medicine’s leadership in gene editing and cardiovascular care.”
The Smilow Foundation’s recent philanthropy builds upon its previous support of Penn Medicine to create the Smilow Center for Translational Research and the William Smilow Professorship, which reflects their deeply rooted commitment to supporting impactful medical research. The Professorship, founded in 2012 by William Smilow and his father the late Joel Smilow, was created as part of their landmark gift to name the Smilow Center for Translational Research, an integral part of Penn’s medical campus that has become one of the nation’s premier research facilities.
“The impact of philanthropy extends far beyond a single moment. Through their remarkable generosity, the Smilow Foundation is helping to fuel innovation and accelerate discoveries that will change the trajectory of cardiovascular medicine. William Smilow has already contributed immeasurably to our remarkable success in translating scientific discoveries into treatments, and this new gift is equally visionary,” said Penn President J. Larry Jameson.
“Heart disease has touched my family personally, which makes this mission genuinely meaningful to me,” said William Smilow, President and CEO of the Smilow Foundation. “The creation of the Smilow Center for Precision Therapeutics reflects our commitment to advancing the science needed to cure heart disease and spare future generations from its impact. As a Penn Medicine Board member and longtime partner, I am confident there is no institution better positioned than Penn to turn that vision into reality.”
Penn Medicine is at the forefront of studying and treating cardiovascular diseases, as well as genetics, gene therapies, and precision medicine. Under the leadership of Thomas P. Cappola, the William Smilow Professor, Division Chief of Cardiovascular Medicine and center director, the Smilow Center for Precision Therapeutics aims to develop curative therapies for heart disease for the first time and will leverage Penn-led discoveries and expertise through innovative research, first-in-human clinical trials, and world-class patient care.
The Smilow Foundation’s philanthropy will enable experts from a broad range of disciplines to develop a roadmap to bring new treatments to patients for the first time. The Smilow Center’s highly collaborative and multidisciplinary environment brings together experts from Penn Medicine’s departments of cardiovascular medicine, physiology, systems pharmacology and translational therapeutics, bioengineering, radiology, and others to deliver unparalleled expertise across all aspects of cardiovascular disease. It will leverage the command of pioneers like Kiran Musunuru and Drew Weissman in breakthrough technologies like CRISPR and mRNA. For example, Musunuru, the Barry J. Gertz Professor for Translational Research, has developed gene-editing therapies to permanently lower cholesterol levels, greatly reducing the risk of heart attack and stroke.
“The launch of the Smilow Center for Precision Therapeutics marks a transformative moment for Penn Medicine and for the future of cardiovascular care,” said Michael Parmacek, chair of the department of medicine and the Frank Wister Thomas Professor of Medicine. “Made possible by the exceptional generosity of the Smilow Foundation and with the visionary leadership of Dr. Cappola, the Smilow Center will build on Penn’s unmatched strengths in cardiovascular science, genetics, gene editing, and translational medicine. More than expanding existing programs, it will create entirely new scientific and clinical capabilities that accelerate discovery, attract world-class talent, and bring personalized therapies to patients with unprecedented speed and precision. The Smilow Center positions Penn to become the nation’s leading destination for cardiovascular translational research and innovation.”
The Smilow Foundation’s primary areas of interest are medical research and education, with leadership gifts to institutions such as Yale’s Smilow Cancer Hospital and New York University’s Langone Medical Center. The Foundation is a founding donor of the Smilow Woodland TGR Learning Lab at the revitalized Cobbs Creek Golf Course in West Philadelphia. William Smilow is a member of the Penn Medicine Board, as well as the Penn Cardiovascular Institute Leadership Council, and Penn Medicine Development Leadership Cabinet. He also serves as a board member for the TGR Foundation and the Cobbs Creek Foundation.
“We are grateful to the Smilow Foundation for their remarkable generosity and vision,” said Kevin B. Mahoney, chief executive officer of the University of Pennsylvania Health System. “By bringing together experts from across disciplines through the Smilow Center for Precision Therapeutics, Penn Medicine is uniquely positioned to pioneer new approaches to treating, and ultimately curing, heart disease, accelerating the delivery of groundbreaking therapies to patients everywhere.”
Camille Hosman: Assistant Vice President of Federal Affairs
Camille Hosman, ML’23, has been appointed Penn’s assistant vice president of federal affairs in the Office of Government and Community Affairs. Based in Washington, D.C., Ms. Hosman is responsible for Penn’s strategic advocacy on policies affecting the University and higher education. She advises Penn leadership on legislative and regulatory developments and represents Penn to Congress, federal agencies, and higher education coalitions.
Ms. Hosman most recently worked as the director of federal government affairs at Stanford University, where she supported engagement with policymakers, specializing in matters related to scientific research, education, and immigration, as well as critical and emerging technology issues. Before her position at Stanford, Ms. Hosman served as the associate director of federal affairs at Penn. Formerly, she led government relations for the Consortium of Social Science Associations and worked for the University of Missouri System Office of Government Relations.
Ms. Hosman is deeply engaged in the federal research and higher education advocacy community. This year, she chaired the Association of American Universities (AAU) Council on Federal Relations Innovation Task Force, coordinating advocacy efforts for the National Science Foundation, NASA, the Department of Defense, the Department of Energy, and the Agriculture and Food Research Initiative. In 2023, the AAU Council on Federal Relations honored Ms. Hosman with the New Innovator Award, an award for council members who have served fewer than five years and made significant contributions to the AAU federal relations community. She has also served on the Board of Directors for the Science Coalition.
Ms. Hosman holds a bachelor of arts in political science from the University of Missouri and a master of law from the University of Pennsylvania. She serves on the Board of Advisors of the Truman School of Government and Public Affairs at the University of Missouri.
Leadership Gift to Penn Carey Law from the Perry and Donna Golkin Family Foundation
The University of Pennsylvania Carey Law School has announced a leadership gift from the Perry and Donna Golkin Family Foundation, established by Perry Golkin, W’74, WG’74, L’78, and Donna Golkin, WG’77, to advance legal education and scholarship at the intersection of law and technology.
“The Golkins’ generosity has long played a critical role in strengthening Penn’s leadership in transformative legal education, and their gift will allow us to remain at the forefront of law and technology,” said Penn President J. Larry Jameson. “We are deeply grateful for their commitment to advancing the University’s strategic priorities and the Law School’s mission.”
The Golkins’ gift serves as a catalyst for Technology, Regulation, AI, and the Law (TRAIL), a key initiative that brings together the school’s growing curriculum, experiential learning opportunities, and faculty research at the forefront of legal education and scholarship in artificial intelligence, emerging technology, and law.
“This foundational gift allows Penn Carey Law to build on our existing strength in law and technology, bring our many efforts under one banner, and position the Law School to continue evolving to meet this moment,” said Sophia Z. Lee, Dean and Bernard G. Segal Professor of Law. “We are very grateful for the Golkins’ support and the extraordinary opportunity it creates.”
Perry Golkin, former chair and current member of the Board of Advisors at the school and an emeritus Penn Trustee, and Donna Golkin have a long history of supporting Penn Carey Law. Their philanthropy includes lead gifts for Golkin Hall, a major addition to the school’s campus that expanded and connected its academic spaces, as well as support for the Perry Golkin Professorship, currently held by Elizabeth Pollman, and the Golkin Family Professorship, currently held by deputy dean Tess Wilkinson-Ryan.
“Penn Carey Law has built real momentum at the intersection of law and technology, from CTIC’s groundbreaking research, to a faculty with expertise spanning disciplines and industries, to a curriculum now preparing every student to practice in an AI-driven profession,” said Perry Golkin. “My hope is that this gift serves as an anchor for that work—one that inspires others to invest alongside us—so that Penn Carey Law can continue recruiting and supporting faculty at the forefront of this field, expanding how it’s taught, and leading the conversation on questions technology is raising for law, work, and society today and in the future.”
The gift will be split between two distinct funds, with one supporting research and scholarship through the Center for Technology, Innovation, and Competition (CTIC). Established in 2007, CTIC leads initiatives around law, technology, and markets, partnering across the Penn community to address the complex legal questions raised by emerging technologies such as artificial intelligence.
“This gift allows CTIC to deepen its work at exactly the moment when it matters most, as AI, international competition, and even the governance of outer space are testing the boundaries of existing legal frameworks,” said Christopher S. Yoo, the Imasogie Professor in Law and Technology and founding director of CTIC. “Rigorous, evidence-based research is essential to understanding these developments and their implications for law and policy. This support allows us to examine these questions in greater depth and provide a stronger foundation for decision-making by policymakers, industry, and the legal community.”
The gift also enables the creation of a Dean’s Innovation Fund, which will provide flexible resources for Penn Carey Law’s broader initiatives in law and technology.
The Golkins’ support arrives at a time of increased momentum surrounding scholarship and curriculum to advance the field of law and technology at the school. Faculty scholarship reflects the school’s distinctive interdisciplinary strengths, bringing together multiple fields and modes of inquiry to examine legal practice and the legal and regulatory questions raised by new technologies.
Penn Vet Breaks Ground on $94 Million Pennsylvania-Funded Veterinary Diagnostic Laboratory at New Bolton Center
When a flock or herd shows signs of illness, or a racehorse tests positive for a banned substance, the accuracy and speed of laboratory results can determine the outcome for animals, livelihoods, and public health. A new state-funded diagnostic laboratory broke ground on October 2 at New Bolton Center, Penn Vet’s large animal campus in Chester County, designed to deliver those results faster and to accelerate research in a purpose-built space.
The $94 million, 63,000-square-foot Veterinary Diagnostic Laboratory (VDL), sponsored by the Pennsylvania Department of Agriculture, will bring together the New Bolton Center laboratory of the Pennsylvania Animal Diagnostic Laboratory System (PADLS) and the Pennsylvania Equine Toxicology Research Laboratory (PETRL), which serve producers, public health officials, veterinarians, regulators, and racing officials across the state.
Both laboratories have outgrown their current homes. The PADLS laboratory at New Bolton Center, which performed more than 279,000 diagnostic tests last year, operates in laboratory spaces spread across several buildings on the center’s upper and lower campuses, with no room to innovate, grow, or consolidate. PETRL typically tests 30,000 samples a year from six Pennsylvania racetracks and leads research in drug testing, even as it works from leased space at West Chester University and research space at New Bolton Center. The new VDL will provide analytical and research laboratories designed for each program’s current work, with space to expand.
“For years, our diagnostic and toxicology teams have delivered results that people across Pennsylvania rely on,” said Andrew M. Hoffman, the Gilbert S. Kahn Dean of Penn Vet. “The Veterinary Diagnostic Laboratory will put them side by side in modern facilities, where collaboration is part of the daily workflow. The Commonwealth’s investment gives the science that protects Pennsylvania’s animals, agriculture, and public health a home equal to its importance.”
The VDL reflects Pennsylvania’s commitment to agriculture, a sector that includes more than 48,800 farms, contributes over $132 billion a year to the state’s economy, and supports nearly 600,000 jobs.
“Science continues to reveal critical connections between animal health, human health, and the health of our environment,” said Russell Redding, Pennsylvania Secretary of Agriculture. “Penn Vet has been at the center of discovery that deepens and reinforces those connections. Supporting Penn Vet’s cutting-edge research, diagnostic testing, and quality animal care strengthens Pennsylvania’s capacity to detect and prevent disease, respond quickly in crisis, and continue growing and leading in animal agriculture. This expansion is more proof that investments by the [Pennsylvania Governor Josh] Shapiro Administration are feeding Pennsylvania’s economic future and protecting Pennsylvania’s rich agricultural heritage.”
The Commonwealth of Pennsylvania established PADLS in 1991 to protect animal and human health and minimize agricultural economic loss across the state. The New Bolton Center laboratory is one of four state laboratories in the system, along with the Pennsylvania Department of Agriculture’s Pennsylvania Veterinary Laboratory in Harrisburg and Penn State’s laboratories in University Park and western Pennsylvania. The New Bolton Center, Harrisburg, and University Park facilities are members of the National Animal Health Laboratory Network (NAHLN) and accredited by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). As the newest member of PADLS, Penn State’s other facility in western Pennsylvania will work toward its NAHLN membership and AAVLD accreditation.
PETRL analyzes post-race samples collected following competition, as well as out-of-competition samples used to screen horses in training for substances that compromise the integrity of racing and the welfare of the horse. With research funding from the commonwealth and other generous donors, PETRL has become the only laboratory in the United States that is accredited to test for gene doping and the only laboratory in the country that is capable of confirming the presence of blood-doping agents such as erythropoietin (EPO) and darbepoetin (DPO). PETRL adheres to the international ISO/IEC 17025 accreditation standard and is dual-accredited by the Racing Medication Testing Consortium and the American Association for Laboratory Accreditation.
Construction of the VDL is expected to be completed in 2028, with both laboratories moving into the new building in 2029. The architect for the project is SMP Architects. Once open, the laboratory will be a dedicated home for the diagnostic and toxicology work that Pennsylvania’s agricultural and equine communities depend on and will give Penn Vet’s scientists the capacity to build on it for decades to come.
SP2 Launches Center for Advancing Research and Education on Social Care (CARES)
Penn’s School of Social Policy & Practice (SP2) has launched the Center for Advancing Research and Education on Social Care (CARES), a new center dedicated to strengthening the evidence, workforce, and research infrastructure needed to advance social care and healthcare social work. The center is a strategic partnership among SP2, the Hospital of the University of Pennsylvania (HUP), and the Children’s Hospital of Philadelphia (CHOP).
Social workers play an essential role across the healthcare continuum, supporting patients, families, and communities while helping health systems address increasingly complex social and behavioral health needs. Yet the full scope and impact of their contributions are not always measured or widely recognized. Directed by Abigail Ross and Tamara Cadet, CARES was established to address that gap by building research capacity, creating educational and professional development opportunities, and fostering collaboration across health systems. By leveraging the strengths of SP2, HUP, and CHOP, CARES seeks to create models that can strengthen healthcare social work locally and be replicated nationally.
CARES is focused on three primary goals:
- Building capacity for social work research, practice, and professional development within and across health systems.
- Generating evidence that demonstrates the value and impact of social work on health outcomes, patient experience, and healthcare delivery.
- Developing educational and workforce initiatives that prepare current and future social workers to meet the evolving needs of patients, families, and health systems.
To achieve these goals, CARES supports efforts to strengthen research infrastructure, develop practice-based research networks, evaluate innovative models of social care, expand continuing education opportunities, and create interdisciplinary learning experiences for SP2 Master of Social Work (MSW) students.
The center’s work is anchored by several signature programs that are designed to support healthcare social workers at every stage of their careers. These include the Social Work Affiliates Program, a two-year professional development initiative that recognizes selected HUP and CHOP social workers with a formal academic affiliation with SP2 and provides them with mentorship, infrastructure, collaborative learning opportunities, and instrumental support to develop research initiatives that demonstrate the value of social work in healthcare settings.
CARES also oversees the Dean’s Research Fellows Program, which pairs first-year SP2 MSW students with social work affiliates to participate in pragmatic research and quality improvement projects focused on healthcare settings.
In addition, the center supports the Behavioral Health Workforce Education and Training (BHWET) Fellowship, funded through the Health Resources and Services Administration in partnership with CHOP. This interdisciplinary fellowship prepares second-year SP2 MSW students to deliver integrated behavioral health services in pediatric healthcare settings alongside colleagues from other disciplines.
CARES will also support the National Consortium of Pediatric Health Care Social Work Leadership, which was launched by SP2 and CHOP in 2025 to advance leadership development, research, innovation, and best practices across social work departments situated within top pediatric health systems nationwide.
SP2 celebrated the launch of CARES during a reception held on September 15 that brought together members of the National Consortium of Pediatric Health Care Social Work Leadership, SP2 social work affiliates, Dean’s Research Fellows, BHWET alumni and current fellows, as well as other colleagues, educators, practitioners, and partners in healthcare social work from across the country.
In remarks at the event, SP2 Dean Sara S. Bachman emphasized the critical role social workers play in healthcare systems and the importance of investing in the profession’s future.Dean Bachman noted that CARES represents a commitment to connecting academic, clinical, and operational expertise to strengthen practice, build evidence, and demonstrate impact across health systems. “Together, we will make social work a strategic capability that shapes the future of healthcare,” Dean Bachman said.
In the coming months, the center will announce its inaugural cohorts of social work affiliates and Dean’s Research Fellows, as well as the second cohort of BHWET Fellows, further strengthening the pipeline of healthcare social work leaders, researchers, and innovators.
Penn GSE Launches Living Laboratory for Human Agency and AI (Living Lab)
As artificial intelligence rapidly reshapes teaching and learning, educators, schools, and policymakers are grappling with how to harness its benefits while protecting students and preserving what matters most about education. To help answer those questions, the University of Pennsylvania Graduate School of Education (Penn GSE) is launching the Penn GSE Living Laboratory for Human Agency and AI (Living Lab).
Building on Penn GSE’s leadership in AI and education, the initiative brings together researchers, educators, school systems, and industry partners to develop approaches to AI in real-world educational settings. Designed as a network rather than a standalone center, the Living Lab will serve as a hub for rapid evidence-based innovation and collaboration on the future of learning—while helping educators and policymakers address emerging questions about the safe and responsible use of AI in education.
“Artificial intelligence presents tremendous opportunities for learning, but it also raises important questions about safety, trust, and how these tools should be used,” said Katharine O. Strunk, Dean of Penn GSE and the George and Diane Weiss Professor of Education. “Too often, education systems and educators are asked to respond to technological change after the fact. The education community has a critical role to play in determining how artificial intelligence develops and how it is used. The decisions being made today will influence how students learn, how teachers work, and how opportunity is distributed for years to come.”
“Educators are experimenting with AI every day, often without clear guidance about what works, for whom, and under what conditions,” said Bodong Chen, director of the Knowledge Building Innovation Network at Penn GSE and founding co-director of the Living Lab. “Schools need more than predictions about what AI might do. We want educators and students to be the designers of AI in learning, not just its users, and to build the evidence of what their designs make possible. That is how we keep learning human.”
The Living Lab focuses on five priorities:
- People First: Ensuring AI enhances human agency and learning.
- Trust, Safety, and Ethics: Advancing responsible AI practices that protect privacy, security, and learner well-being.
- Practice-Driven Innovation: Co-designing and testing AI tools in authentic educational settings.
- AI Literacy and Pedagogy: Advancing effective and trustworthy AI use among educators and students.
- Infrastructure for Scale: Building the partnerships and systems needed to sustain innovation.
The new hub builds on Penn GSE’s growing portfolio of AI-related teaching, research, and innovation, creating an interdisciplinary foundation for the initiative. Across the school, faculty are developing and studying approaches that put educators and learners at the center of how AI is designed, used, and evaluated.
“For the first time, we have the ability to understand and support learning at a level of scale and personalization that was previously impossible,” said Seiji Isotani, faculty director of the Learning Analytics and Artificial Intelligence program and founding co-director of the Living Lab. “The challenge is ensuring these advances are grounded in learning sciences and designed to serve learners. By combining expertise in AI, learning analytics, and learning sciences, we can help unlock that potential while addressing the challenges that come with it.”
Alongside Penn AI and the University’s strengths in medicine, engineering, business, and the social sciences, Penn GSE is helping ensure that education plays a central role in shaping the future of artificial intelligence. The Living Lab helps translate emerging research into practical tools, partnerships, and insights for schools.
Through three years of philanthropic support, the Living Lab will help launch new research, deepen partnerships with schools, and create opportunities for students to work on pressing questions. Potential projects could include evaluating AI tutoring tools, developing resources to help educators use AI responsibly, studying the impact of AI on teaching and learning, or testing strategies to improve AI literacy among students and teachers.
In addition, the Living Lab will host a Google Public Sector-supported speaker series, bringing leading experts from industry, education, and the nonprofit sector to campus to share and interrogate emerging ideas and best practices. While these opportunities will focus primarily on Penn GSE students, they will also be open to students across the University of Pennsylvania, reflecting the Living Lab’s commitment to interdisciplinary collaboration and broad engagement.