Honors & Other Things

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NSF CAREER Award: Dr. Raj

A. Raj

Arjun Raj, assistant professor in the department of bioengineering in the School of Engineering & Applied Science, is the recipient of an NSF CAREER Award for his proposal, “Unraveling Homeostatic Mechanisms in Gene Expression Regulation: Integrating Research and Scientific Communication.” The CAREER Award is the NSF’s most prestigious award in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of education and research within the context of the mission of their organizations.

Dr. Raj’s research works to develop a quantitative understanding of molecular underpinnings of cellular behavior and then uses this knowledge to better human health. In the “Raj Lab” he combines new tools that he and his collaborators have developed for single cell imaging with new genomic and computational methods to make highly accurate measurements of the molecular components underlying cellular function, focusing in particular on the behavior of single cells within an ensemble.

 

 

Kaufman Foundation Grant: Drs. Sweeney and Kamien

A. Sweeney R. Kamien  

A pair of University of Pennsylvania physicists will receive one of the nine grants being awarded this year by the Charles E. Kaufman Foundation, part of The Pittsburgh Foundation, which supports cutting-edge scientific research in chemistry, biology and physics at institutions across the Commonwealth of Pennsylvania.

Assistant professor Alison Sweeney and professor Randall Kamien, both of the department of physics & astronomy in Penn’s School of Arts & Sciences, will receive $300,000 over two years to study living optical devices, or structures within animals that have evolved to shape and direct light in ways that may surpass advanced human technologies.

These animals, including squids and octopuses, naturally incorporate a type of protein called “reflectin” into a variety of structures within their bodies. The reflectin found in certain squids’ cells creates a kind of biological reflector with features smaller than the wavelength of visible light. This enables them to change the amount and color of light their bodies reflect as they move into brighter or darker waters, providing camouflage.       

Another species that incorporates reflective proteins, giant clams, has an even more innovative application for them.
“The giant clams use these sub-wavelength structures to optimize the photosynthesis of the algae living in their tissues,” Dr. Sweeney said. “They are essentially farming the algae for nutrients.”

Understanding how these structures assemble themselves into arrangements that make these abilities possible requires an interdisciplinary approach, drawing on evolutionary theory, biochemistry, photonics and soft matter physics. Dr. Sweeney, a biologist by training, and Dr. Kamien, a theoretical physicist who works in the field of self-assembly and soft condensed matter, represent a unique combination of the skill sets necessary to undertake such a study.  

“Penn is special,” Dr. Kamien said, “in that researchers of our diverse backgrounds can work down the hall from one another and come together to answer these interesting questions.”

Dr. Kamien and Dr. Sweeney are members of Penn Arts & Sciences’ Evolution Cluster, which is organized to encourage this type of broadly interdisciplinary research around a common theme. 

 

 

 

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