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Center for Therapeutic Effectiveness Research: Funds for Pilot Studies: February 29

January 24, 2012, Volume 58, No. 19

The Center for Therapeutic Effectiveness Research (CTER) will fund several one-year pilot projects beginning in June, 2012 to support research aligned with its mission. Newly established with funding from the Perelman School of Medicine’s Center for Clinical Epidemiology and Biostatistics and department of medicine, CTER aims to improve public health through enhancement of the effectiveness of currently available therapies (including medications, devices, and vaccines). CTER engages in multidisciplinary efforts to address the challenges of developing and testing interventions to improve effectiveness and determining strategies to implement these methods in practice. Dr. Stephen Kimmel, professor of medicine in the cardiovascular division and professor of epidemiology in the department of biostatistics and epidemiology, is the founding director of CTER.

Pilot studies should consist of either the design of an intervention that would subsequently lead to a clinical trial or a pilot clinical trial that would lead to a larger scale intervention. Research questions must focus on therapeutics (including medications, devices, or vaccines) and be in one of four areas: 1) methods for performing clinical effectiveness trials, 2) adherence, 3) personalized medicine (e.g., pharmacogenetics), or 4) implementation strategies. Within these four areas, the following are particular topics of interest: patient adherence; choice, dosing or monitoring of medication; prescriber behavior; pharmacogenetics; transition of care interventions; and clinical trial methods development.

It is expected that pilot study data will serve as the basis for future extramural funding and continued involvement with CTER.

Award: Each pilot study will be funded up to $25,000, for personnel and/or other study costs.

Eligibility:  Principal Investigators must be Penn faculty members or predoctoral/postdoctoral fellows with a primary faculty mentor.

Review Process:  Applications will be evaluated by a scientific review group for their relevance to CTER objectives, scientific merit, and potential for future extramural funding.  Deadline for applications is February 29, 2012and selected applicants will be notified in April 2012.

For more information on the application process, go to www.med.upenn.edu/cter

For questions email sabarile@mail.med.upenn.edu

Almanac - January 24, 2012, Volume 58, No. 19